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Results for search "Clinical Trials".

20 Jul

Early Study Finds Experimental Shot Helps Lower Blood Pressure for Months

Patients given a single shot of a new hypertension drug saw their upper and lower BP numbers drop for a prolonged period of time, according to the results of a phase clinical trial.

Health News Results - 254

10 Oct
Experimental Drug Could Rein in Epilepsy Seizures

Experimental Drug Could Rein in Epilepsy Seizures

For people with tough-to-treat epilepsy, seizures can be both frightening and dangerous, but a new experimental pill may bring significant relief to over one-third of them.

Dubbed XEN1101, the new drug reduced the frequency of seizures by more than 50%, or even eliminate...

05 Oct
Ketamine Nasal Spray Shows Promise Against Tough-to-Treat Depression

Ketamine Nasal Spray Shows Promise Against Tough-to-Treat Depression

A nasal spray containing a ketamine derivative appears to beat one of the standard drugs used for people with difficult-to-treat depression, a new clinical trial has found.

The trial, of nearly 700 people with treatment-resistant depression, found that esketamine nasal s...

04 Oct
Stem Cell Therapy Could Be Breakthrough Against Type 1 Diabetes

Stem Cell Therapy Could Be Breakthrough Against Type 1 Diabetes

People with type 1 diabetes lack functional islet cells in their pancreas to produce the hormone insulin and must take daily insulin via injections or a continuous pump to compensate.

But if

20 Jul
Experimental Shot Given Every Six Months Controlled High Blood Pressure in Early Trial

Experimental Shot Given Every Six Months Controlled High Blood Pressure in Early Trial

Every day, millions of people must take one or more pills to control their blood pressure and reduce their risk for heart attack or stroke, but if new research pans out, some may be able to scrap their pills for a twice-yearly shot with the same benefits.

Given as a shot...

17 Jul
Experimental Alzheimer's Drug Slows Thinking Declines in Late-Stage Trial

Experimental Alzheimer's Drug Slows Thinking Declines in Late-Stage Trial

Another experimental drug meant to slow the damage of Alzheimer's appears poised to join a growing arsenal of new treatments for this memory-robbing disease.

In research published online Monday in the

13 Jul
Low-Dose Eyedrops No Better Than Placebo for Nearsightedness Among Kids

Low-Dose Eyedrops No Better Than Placebo for Nearsightedness Among Kids

Low doses of the eyedrops ophthalmologists use to dilate your pupils during an eye exam are not able to slow the progression of nearsightedness (myopia) in children, a new clinical trial has found.

Atropine eyedrops at a concentration of 0.01% did not outperform placebo ...

06 Jul
FDA Gives Full Approval to Alzheimer's Drug Leqembi

FDA Gives Full Approval to Alzheimer's Drug Leqembi

The U.S. Food and Drug Administration on Thursday gave full approval to the Alzheimer's drug Leqembi, clearing the way for insurance coverage of the pricey drug.

“The full FDA approval will open the floodgates for people with early Alzheimer's to get this drug. It's a ...

27 Jun
New Competitor to Wegovy Shows Promise in Clinical Trials

New Competitor to Wegovy Shows Promise in Clinical Trials

An experimental drug appears to outperform the trendy medications Wegovy and Ozempic for both weight loss and diabetes control, a pair of early clinical trials shows.

Retatrutide helped people with obesity drop about one-quarter of their starting weight, on average, duri...

12 Jun
Antibody Treatment Could Fight Rare But Deadly Bile Duct Cancers

Antibody Treatment Could Fight Rare But Deadly Bile Duct Cancers

Patients with bile duct cancer might soon have an additional treatment available to them, thanks to a newly discovered tumor target.

Some bile duct cancers are driven by a mutated HER2 gene, which has also been implicated in cancers of the breast, esophagus and prostate,...

12 Jun
More Evidence Gene Therapy Might Cure Sickle Cell Disease

More Evidence Gene Therapy Might Cure Sickle Cell Disease

A clinical trial that's attempting to discover a cure for sickle cell disease has found a new gene therapy to be safe and successful in four patients.

Two of the patients were treated at Cleveland Clinic Children's in Ohio, and doctors there are hopeful that their positi...

09 Jun
Diabetes Med Metformin Might Help Prevent Long COVID

Diabetes Med Metformin Might Help Prevent Long COVID

A safe, generic diabetes pill can help people avoid long COVID, a new clinical trial shows.

Metformin cut the risk of long COVID by about 40% for patients who received a two-week course of the drug while battling their infection, the researchers reported.

The ...

07 Jun
Patients With Bladder Cancer May Avoid Removal of Extra Lymph Nodes, Study Finds

Patients With Bladder Cancer May Avoid Removal of Extra Lymph Nodes, Study Finds

For years, doctors have thought that a more extensive surgery that removes a wider swath of lymph nodes was the best option for certain patients with bladder cancer. Now, a new clinical trial is upending that belief.

Researchers found that the strategy — known as exte...

06 Jun
Gene-Targeted Drug Tagrisso Cuts Death Rate in Half for Patients With Early-Stage Lung Cancer

Gene-Targeted Drug Tagrisso Cuts Death Rate in Half for Patients With Early-Stage Lung Cancer

Once-a-day use of the targeted cancer pill Tagrisso (osimertinib) cut the five-year death rate in half for a subset of patients with early-stage lung cancer, a new clinical trial shows.

The results could have major implications for patients whose cancers carry a mutation...

06 Jun
Could a Nitroglycerin Patch Ease Hot Flashes?

Could a Nitroglycerin Patch Ease Hot Flashes?

A new study on using nitroglycerin patches to help women with frequent hot flashes caused by menopause has delivered mixed results.

The benefits of wearing these patches — long used as chest pain medication — were modest. They also were short-lived, with any benefit...

05 Jun
New Drug Could Be Advance Against Glioma Brain Tumors

New Drug Could Be Advance Against Glioma Brain Tumors

An experimental targeted therapy can dramatically slow the progress of common slow-growing brain cancers, a new clinical trial finds.

The oral drug vorasidenib nearly tripled progression-free survival in patients with grade 2 gliomas compared to placebo, nearly 28 months...

02 Jun
Is a Liver Dialysis Device on the Horizon?

Is a Liver Dialysis Device on the Horizon?

A new liver dialysis device might soon be able to save patients on the edge of death from liver failure, early clinical trial results show.

The DIALIVE device safely improved organ function and alleviated symptoms in patients with acute-on-chronic liver failure, compared...

02 Jun
Software Bias Misses Lung Problems in Black Men, Study Finds

Software Bias Misses Lung Problems in Black Men, Study Finds

A common test for lung function may be missing lung problems in Black men, leading to under-diagnosis and insufficient care.

A new study from the University of Pennsylvania estimates that as many as 40% more Black male patients would have been diagnosed with breathing ...

26 Apr
New Form of Levodopa Might Improve Parkinson's Care

New Form of Levodopa Might Improve Parkinson's Care

An extended-release version of a Parkinson's disease drug could provide more stable relief for patients with the movement disorder, new clinical trial data show.

The new formulation of levodopa, called IPX203, extended the duration of patients' “on time" — the amount...

13 Apr
Blood Donors' Gender Doesn't Affect Outcomes for Recipients

Blood Donors' Gender Doesn't Affect Outcomes for Recipients

Whether the gender of a blood donor could affect the recipient's survival was an unanswered question in medicine. Until now.

“Some observational studies had suggested female donor blood might be linked with a higher risk of death among recipients compared to male donor...

03 Apr
Drug Combo Shows Promise Against Advanced Head and Neck Cancer

Drug Combo Shows Promise Against Advanced Head and Neck Cancer

An experimental targeted drug could provide a fresh chance for people with recurring head and neck cancer that has grown resistant to other treatments, a new clinical trial says.

Ficlatuzumab used in combination with the already approved targeted drug cetuximab (Erbitux)...

31 Mar
Monthly Injections Might Lower Bleeding in People With Hemophilia

Monthly Injections Might Lower Bleeding in People With Hemophilia

An experimental injectable drug appears effective in reducing bleeds in patients with hemophilia A and B, according to a pair of new clinical trials.

Two-thirds of people with treatment-resistant hemophilia who were treated with the drug fitusiran had no bleeds at all af...

30 Mar
Doctors Convert Veins Into Arteries to Spare Patients Amputations

Doctors Convert Veins Into Arteries to Spare Patients Amputations

Cynthia Elford had recently lost her left leg to type 1 diabetes, after a sunburned big toe turned nearly black and forced an amputation.

Now, Elford was being told the same thing was happening in her right leg.

“I went to clip the toenail on the big toe of my ri...

20 Mar
New Drug Could Be Treatment Option for People With Eczema

New Drug Could Be Treatment Option for People With Eczema

Patients could soon have access to a new injectable drug to treat atopic dermatitis, the most common form of eczema.

The drug, lebrikizumab, proved effective in teenagers and adults in two clinical trials just published in the

06 Mar
Though Often Prescribed, Diuretic Pills May Not Prevent Kidney Stones

Though Often Prescribed, Diuretic Pills May Not Prevent Kidney Stones

A new study is raising questions about the effectiveness of medications long used to prevent painful kidney stones, but experts say there's no reason for patients to toss their prescriptions out at this point.

Anyone who has ever passed a kidney stone would prefer to avo...

09 Feb
'Neuroprotectant' Drug Could Boost Outcomes After a Stroke

'Neuroprotectant' Drug Could Boost Outcomes After a Stroke

Using a "neuroprotectant" drug alongside the standard surgical removal of a clot may slash the risk of death and disability following a stroke, a new study finds.

The new medication, called ApTOLL, shields brain tissue from continuing damage by cooling down inflamma...

09 Feb
New Injected Drug May Prevent Severe COVID

New Injected Drug May Prevent Severe COVID

A single injection of an experimental biologic drug may cut in half your risk of hospitalization from COVID-19 infection, new clinical trial results show.

Pegylated lambda interferon (PEG-lambda) proved effective against all COVID-19 variants encountered in this internat...

06 Feb
Targeted Drug Tagrisso Could Be Advance Against Lung Cancer

Targeted Drug Tagrisso Could Be Advance Against Lung Cancer

The best treatment for a genetically driven form of lung cancer continues to show lasting benefits, a new clinical trial update shows.

Tagrisso (osimertinib) nearly doubles disease-free survival in earlier-stage patients whose lung cancer is driven by a mutation in their...

06 Jan
FDA Approves Second Alzheimer's Drug, Despite Safety Concerns

FDA Approves Second Alzheimer's Drug, Despite Safety Concerns

The U.S. Food and Drug Administration on Friday approved a second Alzheimer's drug, lecanemab, despite reports of rare brain bleeds linked to use of the drug in some patients.

However, the FDA pointed to the drug's benefits, as well.

“Alzheimer's disease immeasu...

05 Jan
Patients, Doctors Await FDA Decision on Experimental Alzheimer's Drug

Patients, Doctors Await FDA Decision on Experimental Alzheimer's Drug

Lecanemab: It's an experimental medication that's been shown in trials to slow cognitive decline in people with Alzheimer's disease.

It's also up for accelerated approval by the U.S. Food and Drug Administration, with a decision expected by Jan. 6.

However, the d...

08 Dec
Antibody Drug Boosts Survival for Type of Advanced Breast Cancer

Antibody Drug Boosts Survival for Type of Advanced Breast Cancer

A relatively new drug is boosting survival rates for women with a specific type of advanced breast cancer who haven't responded to other treatments, according to a pair of clinical trials.

The targeted antibody drug — trastuzumab deruxtecan (T-DXd, sold under the ...

29 Nov
Second Death in Trial of Experimental Alzheimer's Drug Is Raising Concerns

Second Death in Trial of Experimental Alzheimer's Drug Is Raising Concerns

Two people have now died from brain hemorrhages that may be linked to an experimental Alzheimer's drug, calling into question the medication's safety.

A 65-year-old woman with early-stage Alzheimer's recently died from a massive brain bleed that some researchers link to ...

07 Nov
Amid a Surge in RSV Cases, Hopes for a New Vaccine

Amid a Surge in RSV Cases, Hopes for a New Vaccine

Infants and children sick with RSV are flooding pediatricians' offices and children's hospitals across the United States, due to an early surge of the common childhood virus this year.

But within one or two “sick seasons,” doctors expect to have on hand long-sought t...

04 Nov
Clinical Trials Could Help Stop Alzheimer's. But Who Will Join Them?

Clinical Trials Could Help Stop Alzheimer's. But Who Will Join Them?

New drugs that could slow or prevent the start of dementia would be groundbreaking, but a new poll suggests many middle-aged adults may be reluctant to take part in the studies that test those medications.

Only about 12% of the roughly 1,000 people aged 50 to 64 who were...

26 Oct
Pain Relief in a FLASH: Radiation Treatments Lasting Seconds May Advance Cancer Care

Pain Relief in a FLASH: Radiation Treatments Lasting Seconds May Advance Cancer Care

Flash radiotherapy, a new technology that uses targeted proton beams, is safe and effective in relieving pain for terminal cancer patients, a new, small study suggests.

...

17 Oct
Major Trial of Monkeypox Treatment TPOXX to Launch in Africa

Major Trial of Monkeypox Treatment TPOXX to Launch in Africa

The ability of TPOXX to treat people infected with monkeypox is being directly tested in a new clinical trial in central Africa, U.S. health officials have announced.

TPOXX — t...

10 Oct
Drug Shows Promise Against Autoimmune Disease Scleroderma

Drug Shows Promise Against Autoimmune Disease Scleroderma

Researchers report early success with using an existing rheumatoid arthritis (RA) drug to treat systemic sclerosis, a rare but potentially devastating autoimmune condition.

Th...

03 Oct
Alzheimer's Meds Are Mostly Tested in Whites. That Worries Black Patients, Caregivers

Alzheimer's Meds Are Mostly Tested in Whites. That Worries Black Patients, Caregivers

Larry Griner resigned from his job in California and moved back to his childhood home in Baltimore nearly five years ago so he could care for his mother, Norma.

She had been diagnosed with

28 Sep
New Alzheimer's Drug Shows Promise in Phase 3 Clinical Trial

New Alzheimer's Drug Shows Promise in Phase 3 Clinical Trial

Japanese drugmaker Eisai on Wednesday said its experimental drug lecanemab helped slow thinking declines among people in the early stages of Alzheimer's disease.

The findings from a phase 3...

12 Sep
Screening Test Leads to Fewer Women Included in Autism Studies

Screening Test Leads to Fewer Women Included in Autism Studies

A frequently used screening test for autism creates a gender gap that could hinder diagnosis an...

08 Sep
Experimental Drug Shows Promise Against Lupus

Experimental Drug Shows Promise Against Lupus

An experimental drug that has been shown to treat rashes in people with lupus may also help with lupus-related joint pain.

Affecting as many as 1.5 million people in the United States, lupus is an autoimmun...

25 Aug
New MS Treatment Shows Promise in Trial

New MS Treatment Shows Promise in Trial

An experimental antibody therapy for multiple sclerosis can cut symptom flare-ups by half, versus a standard treatment, a new clinical trial has found.

The drug, called ublituximab, be...

25 Aug
Pill to Counter Lupus Shows Promise in Mouse Study

Pill to Counter Lupus Shows Promise in Mouse Study

An experimental new pill could boost treatment of the autoimmune disease lupus, researchers reported at the American Chemical Society's annual meeting.

The pill has been shown in mouse studies to inhibit lupus symptoms, reverse signs of organ damage, and prevent death, <...

23 Jun
Women Still Underrepresented in Many Clinical Trials

Women Still Underrepresented in Many Clinical Trials

To ensure that all kinds of patients get drugs and devices that are safe and effective for them, they need to be represented in clinical trials, but a new study shows that

15 Jun
Cancer Clinical Trials Make Comeback After Pandemic Slowdown

Cancer Clinical Trials Make Comeback After Pandemic Slowdown

Cancer clinical trials in the United States appear to be rebounding after a significant slowdown during the pandemic, researchers say.

For the study, the investigators analyzed da...

06 Jun
New Weight-Loss Drug Looks Good in Trial

New Weight-Loss Drug Looks Good in Trial

A newly approved drug for type 2 diabetes may be a game-changer for treating obesity, too.

Given as a shot once a week, tirzepatide works on two naturally occurring hormones that help tell the brain that you are full. It may be as effective as weight-loss surgery.

...

06 Jun
In Small Study, New Treatment Brings Remission of Rectal Cancer in All Patients

In Small Study, New Treatment Brings Remission of Rectal Cancer in All Patients

A small study delivers startling results on the power of a new immunotherapy treatment against rectal cancer: The drug triggered remission in all the patients who got it.

...

16 May
Immunotherapy Drug Can Lower Recurrence When Bladder Cancer Spreads

Immunotherapy Drug Can Lower Recurrence When Bladder Cancer Spreads

Immunotherapy with nivolumab (Opdivo) after surgery for metastatic bladder cancer significantly reduces the odds for the tumor's return, a new clinical trial finds.

Among 700 patients with

22 Apr
Tongue Stimulator Shows Promise as Sleep Apnea Treatment in Kids With Down Syndrome

Tongue Stimulator Shows Promise as Sleep Apnea Treatment in Kids With Down Syndrome

Children with Down syndrome are more likely than other kids to have sleep apnea, and existing treatments often fail to work.

Now, an implanted device that stimulates tongue nerves shows promise in reducing their sleep disruptions, a new study finds.

A device calle...

13 Apr
Black Patients Less Likely to Get Into Pancreatic Cancer Clinical Trials

Black Patients Less Likely to Get Into Pancreatic Cancer Clinical Trials

Black Americans are far less likely to be included in clinical trials of pancreatic cancer drugs than white Americans, and eligibility criteria are a significant factor in that gap, according to a new study.

"The standard of care in cancer treatment is informed by studie...

29 Mar
Saving the 'Butterfly Children:' Gene Therapy Helps Heal Deadly Blistering Condition

Saving the 'Butterfly Children:' Gene Therapy Helps Heal Deadly Blistering Condition

An experimental cream-based gene therapy may soon become the first U.S. government-approved means for treating a rare and devastating skin disease that produces "butterfly children."

Patients with recessive dystrophic

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